Supportive care

Therapeutic drug monitoring enables safe and effective lenalidomide therapy in patients with multiple myeloma on hemodialysis. Kobayashi T et al. Ann Hematol. 2016 Sep 6. [Epub ahead of print]. Mid-term outcomes after radiofrequency-targeted vertebral augmentation in the treatment of myeloma associated vertebral fractures. Ali T et al. Technol Health Care. 2016 Sep 14;24(5):745-51. doi: 10.3233/THC-161222. Pharmacokinetics of Cefepime in Patients with Cancer and Febrile…

Complications of myeloma and its treatments

Pathological Fracture In Odontoid Process In Multiple Myeloma. Demirci U et al. Turk J Haematol. 2016 Sep 23. doi: 10.4274/tjh.2016.0020. [Epub ahead of print]. Pinpointing a Factor in Myeloma Bone Disease. [No authors listed]. Cancer Discov. 2016 Sep 22. [Epub ahead of print]. Renal Toxicities of Novel Agents Used for Treatment of Multiple Myeloma. Wanchoo R et al. Clin J Am Soc Nephrol. 2016 Sep 21. pii:…

Current treatments

Upfront autologous stem cell transplantation for newly diagnosed elderly multiple myeloma patients: a prospective multicenter study. Garderet L et al. Haematologica. 2016 Sep 9. pii: haematol.2016.150334. [Epub ahead of print]. Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in patients with newly diagnosed multiple myeloma on the ECOG-ACRIN E4A03 randomized clinical trial: long-term follow-up. Biran N et al. Blood Cancer…

Study reveals prevalence of symptoms in myeloma patients

A Myeloma UK funded study, published recently in the European Journal of Haematology, has found that a large number of symptoms occur frequently in myeloma patients, highlighting the importance of routine assessments throughout the disease trajectory in order to achieve optimal quality of life for patients. Led by Christina Ramsenthaler and Prof Irene Higginson, Department of…

General

Is Maintenance Therapy for Everyone? Nooka AK et al. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S139-44. doi: 10.1016/j.clml.2016.02.011. How to Think About Risk in Myeloma. Krishnan A. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S135-8. doi: 10.1016/j.clml.2016.02.015. Clonal Evolution in Multiple Myeloma. Fakhri B et al. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S130-4. doi: 10.1016/j.clml.2016.02.025. Concise review: Treatment of multiple myeloma in the very elderly: How do novel agents fit in? Kint N et al. J…

Supportive care

Cost-effectiveness analysis of low-molecular-weight heparin versus aspirin thromboprophylaxis in patients newly diagnosed with multiple myeloma. Chalayer E et al. Thromb Res. 2016 Aug 10;145:119-125. doi: 10.1016/j.thromres.2016.08.008. [Epub ahead of print]. Cryotherapy reduces oral mucositis and febrile episodes in myeloma patients treated with high-dose melphalan and autologous stem cell transplant: a prospective, randomized study. Marchesi F et al. Bone Marrow Transplant. 2016 Aug 15. doi:…

Complications of myeloma and its treatments

Chemotherapy treatment of multiple myeloma patients increases circulating levels of endothelial microvesicles. Hall J et al. Thromb Res. 2016 Aug 17;146:20-22. doi: 10.1016/j.thromres.2016.08.017. [Epub ahead of print]. Diarrhea in Multiple Myeloma: A Review of the Literature. Faiman B et al. Clin J Oncol Nurs. 2016 Aug 1;20(4):E100-5. doi: 10.1188/16.CJON.E100-E105. Secondary malignancies in patients with multiple myeloma, Waldenström macroglobulinemia and monoclonal gammopathy of undetermined significance. Castillo…