General

Panobinostat Approved for Multiple Myeloma. [No authors listed. Cancer Discov. 2015 Mar 23. [Epub ahead of print]. American Society of Hematology Annual Meeting 2014: highlights in multiple myeloma. Glavey SV et al. Expert Rev Hematol. 2015 Mar 24:1-3. [Epub ahead of print]. Recent advances in multiple myeloma. Kohgo Y et al. Int J Clin Oncol. 2015 Mar 20. [Epub ahead of print]. Patterns of total cost…

Current treatments

Phase I/II study of melphalan, prednisone and lenalidomide combination for patients with newly diagnosed multiple myeloma who are not candidates for stem cell transplantation. Roy V et al. Blood Cancer J. 2015 Mar 20;5:e294. doi: 10.1038/bcj.2015.23. Phase III trial of bortezomib, cyclophosphamide, dexamethasone (VCD) versus bortezomib, doxorubicin, dexamethasone (PAd) in newly-diagnosed myeloma. Mai EK et al. Leukemia. 2015 Mar 19. doi: 10.1038/leu.2015.80. [Epub…

Complications of myeloma and its treatments

Cytomegalovirus reactivation in patients with multiple myeloma. Hasegawa T et al. Eur J Haematol. 2015 Mar 21. doi: 10.1111/ejh.12551. [Epub ahead of print] Improvement in renal function and its impact on survival in patients with newly diagnosed multiple myeloma. Gonsalves WI et al. Blood Cancer J. 2015 Mar 20;5:e296. doi: 10.1038/bcj.2015.20. Multiple myeloma presenting with a maxillary lesion as the first sign. Ramaiah KK et…

Diagnostic tests and prognostic indicators

Iterative Decomposition of Water and Fat with Echo Asymmetry and Least-Squares Estimation (IDEAL) Magnetic Resonance Imaging as a Biomarker for Symptomatic Multiple Myeloma. Takasu M et al. PLoS One. 2015 Feb 23;10(2):e0116842. doi: 10.1371/journal.pone.0116842. Serum free light chain reduction correlates with response and progression-free survival following carfilzomib therapy in relapsed/refractory multiple myeloma. Vij R et al. Leuk Lymphoma. 2015 Feb 20:1-12. [Epub ahead…

Supportive care

OCTET-CY: a phase II study to investigate the efficacy of post-transplant cyclophosphamide as sole graft-versus-host prophylaxis after allogeneic peripheral blood stem cell transplantation. Holtick U et al. Eur J Haematol. 2015 Feb 23. doi: 10.1111/ejh.12541. [Epub ahead of print]. Use of allogeneic platelet gel in the management of chemotherapy extravasation injuries: a case report. Di Costanzo G et al. Onco…

General

The impact of recent chemotherapy innovation on the longevity of myeloma patients: US and international evidence. Hostenkamp G et al. Soc Sci Med. 2015 Feb 7;130C:162-171. doi: 10.1016/j.socscimed.2015.02.003. [Epub ahead of print]. Multiple myeloma: Updates for pharmacists in the treatment of relapsed and refractory disease. Ashjian E et al. J Oncol Pharm Pract. 2015 Feb 17. pii: 1078155215572036. [Epub ahead of print]. Advance…

Complications of myeloma and its treatments

Management of tumor lysis syndrome in patients with multiple myeloma during bortezomib treatment. Wang L et al. Clin J Oncol Nurs. 2015 Feb 1;19(1):E4-7. doi: 10.1188/15.CJON.E4-E7. Meta-analysis of incidence and risk of peripheral neuropathy associated with intravenous bortezomib. Peng L et al. Support Care Cancer. 2015 Feb 13. [Epub ahead of print]. Renal insufficiency retains adverse prognostic implications despite renal function improvement following…

Supportive care

Plasmapheresis in cast nephropathy: yes or no? Madore F. Curr Opin Nephrol Hypertens. 2015 Jan 14. [Epub ahead of print]. Antimicrobial peptides: an alternative for innovative medicines? da Costa JP et al. Appl Microbiol Biotechnol. 2015 Jan 15. [Epub ahead of print]. Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column. Zadnik PL et al. J…