Biology and Genetics
Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma. Kikuchi S et al. Leukemia. 2015 Mar 24. doi: 10.1038/leu.2015.83. [Epub ahead of print]. Structure-activity relationships of benzhydrol derivatives based on 1′-acetoxychavicol acetate (ACA) and their inhibitory activities on multiple myeloma cell growth via inactivation of the NF-κB pathway. Misawa T et al. Bioorg Med Chem. 2015 Mar 7. pii: S0968-0896(15)00143-1. doi:…