Category Archives: Diagnosing and Monitoring Myeloma

Diagnostic techniques and prognostic indicators

Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test. Heaney JLJ et al. BMC Nephrol. 2017 Jul 20;18(1):247. doi: 10.1186/s12882-017-0661-z. Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma. van Beers EH et al. Clin Lymphoma Myeloma Leuk. 2017 Jul 4. pii: S2152-2650(17)30278-1. doi: 10.1016/j.clml.2017.06.020. [Epub…

Diagnostic techniques and prognostic indicators

Diagnosis and monitoring for light chain only and oligosecretory myeloma using serum free light chain tests. Heaney JLJ et al. Br J Haematol. 2017 Jun 1. doi: 10.1111/bjh.14753. [Epub ahead of print]. Circulating adiponectin levels differ between patients with multiple myeloma and its precursor disease. Hofmann JN et al. Obesity (Silver Spring). 2017 Jun 11. doi: 10.1002/oby.21894. [Epub ahead of print]. Diffusion-weighted whole-body MRI for…

Diagnostic techniques and prognostic indicators

Identification of pathway-based prognostic gene signatures in patients with multiple myeloma. Zamani-Ahmadmahmudi M et al. Transl Res. 2017 May 9. pii: S1931-5244(17)30041-5. doi: 10.1016/j.trsl.2017.05.001. [Epub ahead of print]. Comparative proteomic profiling of sera from patients with refractory multiple myeloma reveals potential biomarkers predicting response to bortezomib-based therapy. Łuczak M, Kubicki T et al. Pol Arch Intern Med. 2017 May 25. doi: 10.20452/pamw.4032. [Epub ahead of…

Diagnostic techniques and prognostic indicators

Serum free light chain quantitative assays: Dilemma of a biomarker. Cigliana G et al. J Clin Lab Anal. 2017 Apr 26. doi: 10.1002/jcla.22243. [Epub ahead of print]. The utility of MASS-FIX to detect and monitor monoclonal proteins in the clinic. Milani P et al. Am J Hematol. 2017 Apr 25. doi: 10.1002/ajh.24772. [Epub ahead of print]. Heavy/light chain ratio for…

Diagnostic tests and prognostic indicators

Diagnostic accuracy of computed tomography-guided biopsy in pathological fractures. Stokes CM et al. ANZ J Surg. 2017 Mar 17. doi: 10.1111/ans.13894. [Epub ahead of print]. Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma. Dutoit JC et al. Skeletal Radiol. 2017 Mar 13. doi: 10.1007/s00256-017-2609-6. [Epub ahead of print]. CXCR4 (CD184) expression on stem cell harvest and…

Diagnostic techniques and prognostic indicators

Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker. Chavan SS et al. Blood Cancer J. 2017 Feb 24;7(2):e535. doi: 10.1038/bcj.2017.12. CD117 (KIT) Is A Useful Marker in The Diagnosis of Plasmablastic Plasma Cell Myeloma. Marks E et al. Histopathology. 2017 Feb 22. doi: 10.1111/his.13196. [Epub ahead of print]. In vivo confocal microscopy of multiple myeloma associated…

Diagnostic techniques and prognostic indicators

Recovery of polyclonal immunoglobulins one year after autologous stem cell transplantation as a long-term predictor marker of progression and survival in multiple myeloma. González-Calle V et al. Haematologica. 2017 Jan 25. pii: haematol.2016.158345. doi: 10.3324/haematol.2016.158345. [Epub ahead of print]. Capillary electrophoresis analysis of N-glycosylation changes of serum paraproteins in multiple myeloma. Kovacs Z et al. Electrophoresis. 2017 Jan 24. doi: 10.1002/elps.201700006. [Epub ahead…

Diagnostic techniques and prognostic indicators

Risk stratification in myeloma by detection of circulating plasma cells prior to autologous stem cell transplantation in the novel agent era. Chakraborty R et al. Blood Cancer J. 2016 Dec 16;6(12):e512. doi: 10.1038/bcj.2016.117. A gene expression inflammatory signature specifically predicts multiple myeloma evolution and patients survival. Botta C et al. Blood Cancer J. 2016 Dec 16;6(12):e511. doi: 10.1038/bcj.2016.118. 68Ga-PSMA PET/CT Imaging in Multiple Myeloma. Sasikumar A et…

Diagnostic techniques and prognostic indicators

Improved MDCT monitoring of pelvic myeloma bone disease through the use of a novel longitudinal bone subtraction post-processing algorithm. Horger M et al. Eur Radiol. 2016 Nov 23. [Epub ahead of print]. Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma. Sawyer JR et al. Leukemia. 2016 Nov 4. doi: 10.1038/leu.2016.253. [Epub ahead of print]. Predictors of inferior clinical outcome in patients with…

Diagnostic techniques and prognostic indicators

Minimal residual disease after transplantation or lenalidomide-based consolidation in myeloma patients: a prospective analysis. Oliva S et al. Oncotarget. 2016 Oct 13. doi: 10.18632/oncotarget.12641. [Epub ahead of print]. The role of 68Ga-DOTA-TATE PET/CT scanning in the evaluation of patients with multiple myeloma: preliminary results. Sonmezoglu K et al. Nucl Med Commun. 2016 Oct 21. [Epub ahead of print]. Whole body magnetic resonance imaging in…