Current treatments

Results of Prospective Randomized, Open Label, Non -Inferiority Study of Tbo-Filgrastim (Granix®) Versus Filgrastim (Neupogen®) in Combination with Plerixafor for Autologous Stem Cell Mobilization in Patients with Multiple Myeloma or Non -Hodgkin Lymphoma. Bhamidipati PK et al. Biol Blood Marrow Transplant. 2017 Aug 7. pii: S1083-8791(17)30619-5. doi: 10.1016/j.bbmt.2017.07.023. [Epub ahead of print]. Multiple myeloma with extramedullary disease: impact of autologous stem…

Complications of myeloma and its treatments

Uterine Extramedullary Plasmacytoma as a Primary Manifestation of Multiple Myeloma. Codorniz A et al. Rev Bras Ginecol Obstet. 2017 Aug 23. doi: 10.1055/s-0037-1605373. [Epub ahead of print]. Autoimmune HIT due to apheresis catheter heparin flushes for stem-cell harvesting before autotransplantation for myeloma. Mian H et al. Blood. 2017 Aug 22. pii: blood-2017-06-788679. doi: 10.1182/blood-2017-06-788679. [Epub ahead of print]. Infectious complications in multiple myeloma receiving autologous…

Biology and genetics

Endothelial progenitor cells in multiple myeloma neovascularization: a brick to the wall. Tenreiro MM et al. Angiogenesis. 2017 Aug 24. doi: 10.1007/s10456-017-9571-8. [Epub ahead of print]. Intracellular light chain crystals in myeloma. Staubach ZG et al. Blood. 2017 Aug 24;130(8):1070. doi: 10.1182/blood-2017-04-779207. Logic programming reveals alteration of key transcription factors in multiple myeloma. Miannay B et al. Sci Rep. 2017 Aug 23;7(1):9257. doi: 10.1038/s41598-017-09378-9. Oncolytic…

Supportive treatments

The Role of Low-dose Anti-thymocyte Globulin as Standard Prophylaxis in Mismatched and Matched Unrelated Hematopoietic Peripheral Stem Cell Transplantation for Hematologic Malignancies. Sakellari I et al. Clin Lymphoma Myeloma Leuk. 2017 Jun 29. pii: S2152-2650(17)30096-4. doi: 10.1016/j.clml.2017.06.008. [Epub ahead of print]. Allogeneic Blood or Marrow Transplantation with Post-Transplantation Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Multiple Myeloma. Ghosh N et al. Biol Blood Marrow…

Related conditions

Congestive Heart Failure with Preserved Ejection Fraction in a Patient with Light Chain (AL) Amyloidosis and Multiple Myeloma. Carrizales-Sepúlveda EF et al. Am J Case Rep. 2017 Jul 13;18:790-793. Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Meziane I et al. Haematologica. 2017 Jul 4. pii: haematol.2017.171108. doi: 10.3324/haematol.2017.171108. [Epub ahead of print]. Monoclonal Gammopathy…

General

Longitudinal validity and reliability of the Myeloma Patient Outcome Scale (MyPOS) was established using traditional, generalizability and Rasch psychometric methods. Ramsenthaler C et al. Qual Life Res. 2017 Jul 27. doi: 10.1007/s11136-017-1660-z. [Epub ahead of print]. The Experience of Myeloma Caregivers During Home-Based Oral Chemotherapy Treatment: A Qualitative Study. Morris M et al. Semin Oncol Nurs. 2017 Jul 24. pii: S0749-2081(17)30045-1. doi: 10.1016/j.soncn.2017.05.010. [Epub ahead…

Emerging treatments

CAR-Ts move beyond B-cell cancers to myeloma. Dolgin E. Nat Biotechnol. 2017 Jul 12;35(7):599-601. doi: 10.1038/nbt0717-599. The potential of ixazomib, a second-generation proteasome inhibitor, in the treatment of multiple myeloma. Brayer J et al. Ther Adv Hematol. 2017 Jul;8(7):209-220. doi: 10.1177/2040620717710171. Epub 2017 Jun 28. Randomized, double-blind, placebo-controlled phase III study of ixazomib plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma: China Continuation…

Diagnostic techniques and prognostic indicators

Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test. Heaney JLJ et al. BMC Nephrol. 2017 Jul 20;18(1):247. doi: 10.1186/s12882-017-0661-z. Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma. van Beers EH et al. Clin Lymphoma Myeloma Leuk. 2017 Jul 4. pii: S2152-2650(17)30278-1. doi: 10.1016/j.clml.2017.06.020. [Epub…