Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma.
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A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway.
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Myxoma Virus Induces Ligand Independent Extrinsic Apoptosis in Human Myeloma Cells.
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Inhibition of Transforming Growth Factor β Activation Diminishes Tumor Progression and Osteolytic Bone Disease in Mouse Models of Multiple Myeloma.
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A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma has Potent Anti-tumor Activity.
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Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma.
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A CD2 high-expressing stress resistant human plasmacytoid dendritic cell subset.
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Inhibition of glucose transporter 1 induces apoptosis and sensitizes multiple myeloma cells to conventional chemotherapeutic agents.
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Association of MDR1 single-nucleotide polymorphisms and haplotype variants with multiple myeloma in Chinese Jiangsu Han population.
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Phagocyte Function Decreases after High-Dose Treatment with Melphalan and Autologous Stem Cell Transplantation in Patients with Multiple Myeloma.
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Ex Vivo Evaluation of the Effect of Regulatory T Cells (Treg) on the Anti-Tumor Activity of Bortezomib in Multiple Myeloma.
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miRNA-29a as a tumor suppressor mediates PRIMA-1Met-induced anti-myeloma activity by targeting c-Myc.
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miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth.
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MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication.
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Myeloma impairs mature osteoblast function but causes early expansion of osteo-progenitors: temporal changes in bone physiology and gene expression in the KMS12BM model.
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Regulation of Sclerostin Expression in Multiple Myeloma by Dkk-1; A Potential Therapeutic Strategy for MyelomaBone Disease.
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RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines.
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Kinetic analysis and molecular modelling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.
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Plasma Thrombin Generation and Sensitivity to Activated Protein C Among Patients With Myeloma and Monoclonal Gammopathy of Undetermined Significance.
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Mevalonate Pathway and Human Cancers.
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Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
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Nuclear TRAF3 is a negative regulator of CREB in B cells.
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Bone marrow infiltration by multiple myeloma causes anemia by reversible disruption of erythropoiesis.
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TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myelomathrough NF-кβ inhibition.
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Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed or Refractory Lymphoid Malignancies.
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Ex vivo and in vivo evaluation of over-expressed VLA-4 in multiple myeloma using LLP2A imaging agents.
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Correlation of Mast Cell Density With Angiogenic Cytokines in Patients With Active Multiple Myeloma.
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Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis.
Fu R et al. Oncotarget. 2015 Dec 30. doi: 10.18632/oncotarget.6796. [Epub ahead of print].

Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma.
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Differential expression of alkaline phosphatase gene in proliferating primary lymphocytes and malignant lymphoid cell lines.
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Cilengitide restrains the osteoclast-like bone resorbing activity of myeloma plasma cells.
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The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival.
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Thromboxane A2 Receptor Inhibition Suppresses Multiple Myeloma Cell Proliferation by Inducing P38/JNK MAP Kinase Mediated-G2/M Progression Delay and Cell Apoptosis.
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A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition.
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Cell adhesion downregulates the expression of Homer1b/c and contributes to drug resistance in multiple myeloma cells.
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Genistein inhibits the proliferation of human multiple myeloma cells through suppression of nuclear factor‑κB and upregulation of microRNA‑29b.
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Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.
Lub S et al. Oncotarget. 2015 Dec 26. doi: 10.18632/oncotarget.6768. [Epub ahead of print].

Profound impact of sample processing delay on gene expression of multiple myeloma plasma cells.
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Single-cell analysis of targeted transcriptome predicts drug sensitivity of single cells within human myelomatumors.
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Dexamethasone treatment promotes Bcl-2 dependence in multiple myeloma resulting in sensitivity to venetoclax.
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