The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.
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Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.
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Epigenetic repression of miR-375 is the dominant mechanism for constitutive activation of the PDPK1/RPS6KA3 signalling axis in multiple myeloma.
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Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.
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E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271.
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Selective degradation of splicing factor CAPERα by anticancer sulfonamides.
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MicroRNA Transfer Between Bone Marrow Adipose and Multiple Myeloma Cells.
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Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma.
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Creating artificial lymphoid tissues to study immunity and hematological malignancies.
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A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos.
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DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma.
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Preclinical characterization of BET family bromodomain inhibitor ABBV-075 suggests combination therapeutic strategies.
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Plasma cell myeloma with lymphoplasmacytic morphology and cyclin D1 expression, an uncommon variant.
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PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242.
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NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma.
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An ex vivo platform for the prediction of clinical response in multiple myeloma.
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Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy.
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Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability.
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Ribonucleotide reductase large subunit (RRM1) as a novel therapeutic target in multiple myeloma.
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Interactions between SNPs affecting inflammatory response genes are associated with multiple myeloma disease risk and survival.
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Development of β-Hairpin Peptides for the Measurement of SCF-Family E3 Ligase Activity in Vitro via Ornithine Ubiquitination.
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The t(8;14)(q24.1;q32) and its variant translocations: A study of 34 cases.
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Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments.
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Both mucosal- associated invariant and natural killer T cell deficiency in multiple myeloma can be countered by PD-1 inhibition.
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Bone marrow myeloid cells in regulation of multiple myeloma progression.
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bFGF Polymorphism Is Associated with Disease Progression and Response to Chemotherapy in Multiple Myeloma Patients.
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RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma.
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Abnormal repression of SHP-1, SHP-2 and SOCS-1 transcription sustains the activation of the JAK/STAT3 pathway and the progression of the disease in multiple myeloma.
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PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4.
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Resistin induces multidrug resistance in myeloma by inhibiting cell death and upregulating ABC transporter expression.
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Immunomodulatory activity of microRNAs: potential implications for multiple myeloma treatment.
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The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.
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