Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma. Ludwig C et al. Blood Cancer J. 2015 Oct 16;5:e359. doi: 10.1038/bcj.2015.85. Impact of cytogenetic classification on outcomes following early high dose therapy in multiple myeloma. Kaufman GP et al. Leukemia. 2015 Oct 21. doi: 10.1038/leu.2015.287. [Epub ahead of print]. Insight into human…
DetailsClarification on the definition of complete response in multiple Myeloma. Durie BG et al. Leukemia. 2015 Oct 21. doi: 10.1038/leu.2015.290. [Epub ahead of print]. American Society of Blood and Marrow Transplantation, European Society of Blood and Marrow Transplantation, Blood and Marrow Transplant Clinical Trials Network, and International Myeloma Working Group Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma.…
DetailsFilgrastim versus TBO-filgrastim to reduce the duration of neutropenia after autologous hematopoietic stem cell transplantation: TBO, or not TBO, that is the question. Trifilio S et al. Clin Transplant. 2015 Oct 22. doi: 10.1111/ctr.12637. [Epub ahead of print]. Surgery for vertebral involvement in Multiple Myeloma. Donnarumma P et al. J Neurosurg Sci. 2015 Oct 16. [Epub ahead of print]. Effectiveness of Haemodiafiltration…
DetailsEndobronchial plasmacytoma in patient with multiple myeloma. Sunnetcioglu A et al. Clin Respir J. 2015 Oct 27. doi: 10.1111/crj.12408. [Epub ahead of print]. Rapid Progression of Vascular and Soft Tissue Calcification while Being Managed for Severe and Persistent Hypocalcemia Induced by Denosumab Treatment in a Patient with Multiple Myeloma and Chronic Kidney Disease. Ueki K et al. Intern Med. 2015;54(20):2637-42. doi: 10.2169/internalmedicine.54.4946. Epub 2015…
DetailsSequential versus alternating administration of VMP and Rd in elderly patients with newly diagnosed MM. Mateos MV et al. Blood. 2015 Oct 23. pii: blood-2015-08-666537. [Epub ahead of print]. Bortezomib-thalidomide-dexamethasone (VTD) is superior to bortezomib-cyclophosphamide-dexamethasone (VCD) as induction therapy prior to autologous stem cell transplantation in multiple myeloma. Cavo M et al. Leukemia. 2015 Oct 7. doi: 10.1038/leu.2015.274. [Epub ahead of print].…
DetailsThis study provides evidence that high-dose therapy and autologous stem cell transplantation performed in the outpatient setting can result in excellent outcomes for selected myeloma patients.
DetailsMicroRNAs in urine are not biomarkers of multiple myeloma. Sedlaříková L et al. J Negat Results Biomed. 2015 Sep 23;14(1):16. Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma. Besse L et al. PLoS One. 2015 Sep 21;10(9):e0137294. doi: 10.1371/journal.pone.0137294. Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly…
DetailsExtramedullary plasmacytoma: an unusual neoplasm in a HIV-positive patient.
Joseph AA et al. Int J STD AIDS. 2015 Sep 22. pii: 0956462415605244. [Epub ahead of print].
Synchronous Thyroid Involvement in Plasma Cell Leukemia Masquerading as Hashimoto’s Thyroiditis: Role of Ancillary Cytology Techniques in Diagnostic Workup.
Tandon A et al. Endocr Pathol. 2015 Sep 2. [Epub ahead of print]
A Phase Ib Study of the combination of the Aurora Kinase Inhibitor Alisertib (MLN8237) and Bortezomib in Relapsed Multiple Myeloma. Rosenthal A et al. Br J Haematol. 2015 Sep 25. doi: 10.1111/bjh.13765. [Epub ahead of print]. Carfilzomib, pomalidomide, and dexamethasone (CPD) in patients with relapsed and/or refractory multiple myeloma. Shah JJ et al. Blood. 2015 Sep 17. pii: blood-2015-05-643320. [Epub ahead of print].…
DetailsEpigenetic silencing of a long non-coding RNA KIAA0495 in multiple myeloma. Wong KY et al. Mol Cancer. 2015 Sep 26;14(1):175. 3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma. de la Puente P et al. Biomaterials. 2015 Sep 12;73:70-84. doi: 10.1016/j.biomaterials.2015.09.017. [Epub ahead of print] Transcriptional dysregulation of the deleted in colorectal carcinoma gene in multiple…
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