Pain is one of the most common and debilitating symptoms of progressive myeloma. This guidance written by NICE outlines safe use of opioids for adults with advanced disease.
A Myeloma UK funded study, published recently in the European Journal of Haematology, has found that a large number of symptoms occur frequently in myeloma patients, highlighting the importance of routine assessments throughout the disease trajectory in order to achieve optimal quality of life for patients. Led by Christina Ramsenthaler and Prof Irene Higginson, Department of…Details
IFM (Intergroupe francophone du myélome) recommendations for uniform interpretation of serum and urine protein electrophoresis in multiple myeloma diagnosis and follow-up. Dejoie T et al. Ann Biol Clin (Paris). 2016 Aug 1;74(4):429-441. Application of PET/CT in treatment response evaluation and recurrence prediction in patients with newly-diagnosed multiple myeloma. Li Y et al. Oncotarget. 2016 Aug 19. doi: 10.18632/oncotarget.11418. [Epub ahead of print]. The independent…Details
Gastric Outlet Obstruction due to Gastrointestinal Amyloidosis. Cohen JA et al. J Gastrointest Surg. 2016 Aug 19. [Epub ahead of print]. Paraprotein-Related Kidney Disease: Diagnosing and Treating Monoclonal Gammopathy of Renal Significance. Rosner MH et al. Clin J Am Soc Nephrol. 2016 Aug 15. pii: CJN.02920316. [Epub ahead of print]. Primary pulmonary plasmacytoma: a case report introduction. Nie S et al. World J…Details
New investigational drugs with single-agent activity in multiple myeloma.
Rajan AM et al. Blood Cancer J. 2016 Jul 29;6(7):e451. doi: 10.1038/bcj.2016.53.
Genomic complexity of multiple myeloma and its clinical implications. Manier S et al. Nat Rev Clin Oncol. 2016 Aug 17. doi: 10.1038/nrclinonc.2016.122. [Epub ahead of print]. Baseline characteristics, chromosomal alterations and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma. Merz M et al. Am J Hematol. 2016 Aug 10. doi: 10.1002/ajh.24533. [Epub ahead of print]. Post-Transplant Outcomes in High-Risk Compared with Non-High-Risk Multiple…Details
Is Maintenance Therapy for Everyone? Nooka AK et al. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S139-44. doi: 10.1016/j.clml.2016.02.011. How to Think About Risk in Myeloma. Krishnan A. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S135-8. doi: 10.1016/j.clml.2016.02.015. Clonal Evolution in Multiple Myeloma. Fakhri B et al. Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S130-4. doi: 10.1016/j.clml.2016.02.025. Concise review: Treatment of multiple myeloma in the very elderly: How do novel agents fit in? Kint N et al. J…Details
Cost-effectiveness analysis of low-molecular-weight heparin versus aspirin thromboprophylaxis in patients newly diagnosed with multiple myeloma. Chalayer E et al. Thromb Res. 2016 Aug 10;145:119-125. doi: 10.1016/j.thromres.2016.08.008. [Epub ahead of print]. Cryotherapy reduces oral mucositis and febrile episodes in myeloma patients treated with high-dose melphalan and autologous stem cell transplant: a prospective, randomized study. Marchesi F et al. Bone Marrow Transplant. 2016 Aug 15. doi:…Details