MNLP – Module 4 – Final assessment
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Congratulations on completing Final Assessment 4.
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Question 1 of 20
1. Question
1 point(s)Which of the following is the best single indicator of prognosis at diagnosis of myeloma?
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Question 2 of 20
2. Question
5 point(s)There are a number of prognostic factors in myeloma. Match the words below with their description.
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- Cytogenetic factors
- Plasma cell morphology
- C-reactive protein
- Plasma cell labelling index
- Beta 2 microglobulin
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Chromosomal abnormalities
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Structural features of plasma cells indicate their degree of maturity
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A protein produced by the liver during inflammatory or malignant processes
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The relative percentage of plasma cells actively growing
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A cell surface protein, the levels of which reflect the extent of the disease
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Question 3 of 20
3. Question
1 point(s)When a patient is classified as Stage 2 according to the International Staging system, their likely median survival is
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Question 4 of 20
4. Question
1 point(s)Staging in myeloma is necessary because it
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Question 5 of 20
5. Question
1 point(s)Which of the following is a staging system used in myeloma?
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Question 6 of 20
6. Question
1 point(s)Which of the following is associated with a poorer prognosis
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Question 7 of 20
7. Question
1 point(s)The Durie-Salmon staging system for myeloma includes which of the following factors?
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Question 8 of 20
8. Question
1 point(s)A myeloma patient presents with a haemoglobin level of 80g/l and a serum creatinine of 31mg/l. What stage are they according to the Durie-Salmon staging system?
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Question 9 of 20
9. Question
1 point(s)Which of the following is associated with improved prognosis?
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Question 10 of 20
10. Question
1 point(s)The Intermational staging system for myeloma uses which of the following factors
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Question 11 of 20
11. Question
1 point(s)Which of the following tests is the best single indicator of tumour burden in myeloma?
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Question 12 of 20
12. Question
1 point(s)Patients with the following chromosomal abnormalities are defined as “high-risk” except
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Question 13 of 20
13. Question
1 point(s)Which of the following imaging techniques provides the most useful prognostic information?
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Question 14 of 20
14. Question
1 point(s)Assertion: It is important that patients are accurately staged when entering clinical trials
BECAUSE
Reason: Response to treatment is one of the most important factors that predicts long-term outcome
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Question 15 of 20
15. Question
1 point(s)Assertion: Measurement of minimal residual disease (MRD) is a new concept that is considered to have powerful prognostic significance
BECAUSE
Reason: Patients who are MRD positive are likely to relapse more quickly
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Question 16 of 20
16. Question
1 point(s)Match the terms with the definition.
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- High risk
- Low risk
- Standard risk
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Patients who are ISS stage II/III and have translocation t[4;14] or deletion [17p]
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Patients who are ISS stage I/II, under the age of 55 and who do not have translocation t[4;14] or deletion [17p]
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Patients who are ISS stage II/III and do not have translocation t[4;14] or deletion [17p]
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Question 17 of 20
17. Question
1 point(s)The staging system in myeloma reflects the extent of the disease rather than where it is
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Question 18 of 20
18. Question
1 point(s)Which of the following statements is not true
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Question 19 of 20
19. Question
3 point(s)Fill in the words two, three and four to complete the following
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According to the Durie-Salmon System, there are stages of myeloma based on the presence of main clinical features that reflect the amount and activity of the myeloma. There are three stages in the International Staging System based on the measurement of specific factors.
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Question 20 of 20
20. Question
1 point(s)Measurement of minimal residual disease by flow cytometry is routinely carried out to determine response to treatment.
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