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Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients.
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Assessment of tumoral plasma cells in apheresis products for autologous stem cell transplantation in multiple myeloma.
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MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.
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Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma.
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A novel alkylating agent Melflufen induces irreversible DNA damage and cytotoxicity in multiple myeloma cells.
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Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
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SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma.
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miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.
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Proton pump inhibitors induce a caspase-independent antitumor effect against human multiple myeloma.
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Decreased CD161 activating and increased CD158a inhibitory receptor expression on NK cells underlies impaired NK cell cytotoxicity in patients with multiple myeloma.
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Newly established myeloma-derived stromal cell line MSP-1 supports Multiple Myeloma proliferation, migration, and adhesion and induces drug resistance more than normal-derived stroma.
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Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.
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Involvement of the arachidonic acid cytochrome P450 epoxygenase pathway in the proliferation and invasion of human multiple myeloma cells.
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Opposite activation of the Hedgehog pathway in CD138+ plasma cells and CD138-CD19+ B cells identifies two subgroups of patients with Multiple Myeloma and different prognosis.
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Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
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The effects of cold atmospheric plasma on cell adhesion, differentiation, migration, apoptosis and drug sensitivity of multiple myeloma.
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A Genome-Wide Association Study Identifies a Novel Locus for Bortezomib-Induced Peripheral Neuropathy in European Multiple Myeloma Patients.
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Carfilzomib alters the HLA-presented peptidome of myeloma cells and impairs presentation of peptides with aromatic C-termini.
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Differential effects of lenalidomide during plasma cell differentiation.
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Human platelets repurposed as vehicles for in vivo imaging of myeloma xenotransplants.
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BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth.
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Dual inhibition of oncogenic targets for B-cell malignancies.
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Targeting proteasome ubiquitin receptor Rpn13 in multiple myeloma.
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Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes in particular in redox and energy metabolism.
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A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance inmultiple myeloma cells.
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Targeting CK2-driven non-oncogene addiction in B-cell tumors.
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A transplant immunome deep sequencing and screening platform defines a unique targetable epitope fingerprint of multiple myeloma.
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Gene expression risk signatures maintain prognostic power in multiple myeloma despite microarray probe set translation.
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Therapeutic targeting of miR-29b/HDAC4 epigenetic loop in multiple myeloma.
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