Deazaneplanocin A Is a Promising Drug to Kill Multiple Myeloma Cells in Their Niche.
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HIF-1α inhibition blocks the cross talk between multiple myeloma plasma cells and tumor microenvironment.
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SDF-1 Inhibition Targets the Bone Marrow Niche for Cancer Therapy.
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Antitumor effects of tyropeptin-boronic acid derivatives: new proteasome inhibitors.
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Destabilization of Akt Promotes the Death of Myeloma Cell Lines.
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Low-energy laser irradiation promotes cellular damage in Glucocorticoids-resistant Multiple Myeloma cells.
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Differential and limited expression of mutant alleles in multiple myeloma.
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Genome-wide scan identifies variant in 2q12.3 associated with risk for multiple myeloma.
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MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the anti-myeloma benefit of bortezomib.
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Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway.
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NEK2 mediates ALDH1A1 induced drug-resistance in multiple myeloma.
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pRRophetic: An R Package for Prediction of Clinical Chemotherapeutic Response from Tumor Gene Expression Levels.
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Crosstalk between microRNA30a/b/c/d/e-5p and the Canonical Wnt Pathway: Implications for Multiple Myeloma therapy.
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Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis.
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GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.
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Pyk2 promotes tumor progression in multiple myeloma.
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A HGF/cMET autocrine loop is operative in multiple myeloma bone marrow endothelial cells and may represent a novel therapeutic target.
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A Bim-targeting strategy overcomes adaptive bortezomib-resistance in multiple myeloma through a novel link between autophagy and apoptosis.
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Gene Expression Profiling Identifies IRF4-Associated Molecular Signatures in Hematological Malignancies.
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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.
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MYC deregulation in lymphoid tumors: molecular mechanisms, clinical consequences and therapeutic implications.
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Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma.
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T cell-based targeted immunotherapies for patients with multiple myeloma.
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Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation.
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Activation of LTBP3 Gene by a LncRNA MALAT1 Transcript in Mesenchymal Stem Cells from Multiple Myeloma.
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Seed targeting with tiny anti-miR-155 inhibits malignant progression of multiple myeloma cells.
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Resistance to Chemotherapy: Patient Variability and Cellular Heterogeneity.
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Resistance to Chemotherapy: Patient Variability and Cellular Heterogeneity.
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Inhibition of the MDM2 E3 Ligase Induces Apoptosis and Autophagy in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically with ABT-737.
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Targeting phospho-MARCKS overcomes drug resistance and induces antitumor activity in preclinical models of Multiple Myeloma.
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The effect of the dual PI3K and mTOR inhibitor BEZ235 on tumour growth and osteolytic bone disease in multiple myeloma.
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Dyclonine enhances the cytotoxic effect of proteasome inhibitor bortezomib in multiple myeloma cells.
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Delineating the mTOR Kinase Pathway Using a Dual TORC1/2 Inhibitor AZD8055 in Multiple Myeloma.
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Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking.
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Absolute Quantification of Histone PTM Marks by MRM-Based LC-MS/MS.
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Round cell tumors of bone: an update on recent molecular genetic advances.
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Rush hour traffic: directing T cells to tumor.
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