MNLP – Module 6 – Final assessment

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Question 1 of 20

1. Question

2 point(s)

Match the following words with the correct type of transplantation.

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Allogeneic transplant
Autologous transplant

A transplant involving stem cells from a matched donor is known as an

A transplant involving the patient’s own stem cells is known as an

Correct

Incorrect

Question 2 of 20

2. Question
1 point(s)
Factors normally taken into account when determining the suitability of a patient for high-dose chemotherapy and stem cell transplantation include the following except
- A. Age
- B. Renal function
- C. Lung and cardiac function
- D. Body mass index
- E. Patient preference
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Question 3 of 20

3. Question
1 point(s)
Which of the following statements is not correct?

High-dose chemotherapy followed by stem cell transplantation is used to treat myeloma because it
- A. Provides a greater depth of response than conventional chemotherapy
- B. Provides a greater duration of response than conventional chemotherapy
- C. Can enhance survival
- D. Consolidates the response to induction treatment
- E. Increases the ability of the bone marrow to produce blood cells
Correct

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Question 4 of 20

4. Question
1 point(s)
Can you match the correct term in the sentence

Induction treatment is
- A. Not necessary prior to a stem cell transplant
- B. Treatment involving a high dose of chemotherapy
- C. Treatment given prior to stem cell transplant
- D. Treatment given after stem cell transplant
Correct

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Question 5 of 20

5. Question
1 point(s)
The cells infused during a stem cell transplant are
- A. Pluripotent stem cells
- B. Haematopoietic stem cells
- C. Bone marrow cells
- D. Red blood cells
- E. Embryonic stem cells
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Question 6 of 20

6. Question
1 point(s)
Which new blood cells are stimulated to develop during the process of engraftment?
- A. Red blood cells
- B. Platelets
- C. Neutrophils
- D. Leucocytes
- E. All of the above
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Question 7 of 20

7. Question

4 point(s)

Can you match the correct words to the descriptions below?

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G-CSF
High-dose cyclophosphamide
Mozobil
DMSO

A. A synthetic growth factor which promotes the proliferation and release of stem cells

B. Reduces the number of stem cells temporarily and causes the bone marrow to go into stem cell proliferation overdrive

C. Given when sufficient number of stem cells cannot be mobilised by conventional means

D. A cryoprotectant harvested stem cells are mixed with when stored in liquid nitrogen

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Question 8 of 20

8. Question
1 point(s)
The minimum number of stem cells needed for a transplant is
- A. Half a million stem cells per kg body weight
- B. One million stem cells per kg body weight
- C. Two million stem cells per kg body weight
- D. Three million stem cells per kg body weight
- E. Five million stem cells per kg body weight
Correct

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Question 9 of 20

9. Question
1 point(s)
The most common side-effect of apheresis is
- A. Cramping or tingling sensation
- B. Thirst
- C. Nausea
- D. Loss of appetite
- E. Sore mouth
Correct

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Question 10 of 20

10. Question
1 point(s)
Conditioning treatment involves patients receiving a
- A. A high dose of Velcade
- B. A high dose of melphalan
- C. A high dose of dexamethasone
- D. A high dose of vincristine
- E. A high dose of G-CSF
Correct

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Question 11 of 20

11. Question
1 point(s)
Which of the following is not normally considered a side-effect of high-dose therapy and stem cell transplantation?
- A. Hair loss
- B. Oral mucositis
- C. Myelosuppression
- D. Bone pain
- E. Fatigue
Correct

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Question 12 of 20

12. Question
1 point(s)
The aim of an allogeneic transplant is to generate
- A. Histocompatability
- B. Myeloablation
- C. Immunosuppression
- D. Graft versus host effect
- E. Graft versus disease effect
Correct

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Question 13 of 20

13. Question
1 point(s)
Assertion: The lining of the mouth, the digestive system, skin, hair and bone marrow are most likely to be affected by chemotherapy

BECAUSE

Reason: Chemotherapy particularly affects areas where normal cells are rapidly dividing
- A. True True – reason correctly explains assertion
- B. True True – both statements are true but the reason does not explain the assertion
- C. True False
- D. False True
- E. False False
Correct

Incorrect
Question 14 of 20

14. Question
1 point(s)
Can you match the correct term in the sentence below?

A second transplant is
- A. Usually given within six months of the first
- B. Given as salvage treatment
- C. Always an autologous transplant
- D. Requires more stem cells to be collected
- E. Followed by a donor lymphocyte infusion
Correct

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Question 15 of 20

15. Question
1 point(s)
Assertion: All eligible myeloma patients undergo high-dose chemotherapy and stem cell transplantation

BECAUSE

Reason: Patients must achieve a partial response to induction treatment
- A. True True – reason correctly explains assertion
- B. True True – both statements are true but the reason does not explain the assertion
- C. True False
- D. False True
- E. False False
Correct

Incorrect
Question 16 of 20

16. Question
1 point(s)
Can you match the correct term to the sentence below

The mortality rate for an autologous transplant is – X – the mortality rate for an allogeneic transplant
- greater than
- less than
Correct

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Question 17 of 20

17. Question
1 point(s)
The upper age limit for a patient undergoing an autologous transplant is – X – the upper age limit for a patient undergoing an allogeneic transplant
- greater than
- less than
Correct

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Question 18 of 20

18. Question
1 point(s)
It is recommended that transplant patients only receive irradiated blood products
- A. True
- B. False
Correct

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Question 19 of 20

19. Question
1 point(s)
An autologous transplant is when the donor of the transplant is the sibling of the recipient of the transplant
- A. True
- B. False
Correct

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Question 20 of 20

20. Question
1 point(s)
Which of the following statements is correct?

A tandem autologous transplant is
- A. Also known as a double transplant
- B. Offered to younger/fitter myeloma patients
- C. Given at the time of relapse
- D. Followed by maintenance treatment
Correct

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MNLP – Module 6 – Final assessment