Library – Page 9 – Myeloma Academy

Diagnostic techniques and prognostic indicators

Minimal residual disease after transplantation or lenalidomide-based consolidation in myeloma patients: a prospective analysis. Oliva S et al. Oncotarget. 2016 Oct 13. doi: 10.18632/oncotarget.12641. [Epub ahead of print]. The role of 68Ga-DOTA-TATE PET/CT scanning in the evaluation of patients with multiple myeloma: preliminary results. Sonmezoglu K et al. Nucl Med Commun. 2016 Oct 21. [Epub ahead of print]. Whole body magnetic resonance imaging in…

October 26, 2016Diagnosing and Monitoring Myeloma, Journal, LibraryBy MaggieLai

Palliative care for adults: strong opioids for pain relief (CG140)

Pain is one of the most common and debilitating symptoms of progressive myeloma. This guidance written by NICE outlines safe use of opioids for adults with advanced disease.

Emerging treatments

New investigational drugs with single-agent activity in multiple myeloma.
Rajan AM et al. Blood Cancer J. 2016 Jul 29;6(7):e451. doi: 10.1038/bcj.2016.53.

August 29, 2016Journal, LibraryBy MaggieLai

Haematological cancers: improving outcomes

This NICE guidance covers medical and NHS service recommendations for children and adults who have received a diagnosis of a haematological cancer.

Zoledronic acid treatment at biochemical relapse

This study shows benefits from zoledronic acid monotherapy in myeloma patients with asymptomatic biochemical relapse and suggests that it should be considered as a new standard of care for this group.

October 31, 2015Journal, LibraryBy MaggieLai

Safety of outpatient autologous stem cell transplantation

This study provides evidence that high-dose therapy and autologous stem cell transplantation performed in the outpatient setting can result in excellent outcomes for selected myeloma patients.

September 30, 2015Journal, LibraryBy MaggieLai

IMWG Revised International Staging System (R-ISS) for Multiple Myeloma

The IMWG report on the newly developed revised version of the International Staging System (R-ISS) which incorporates chromosomal abnormalities to develop a more powerful staging system for stratifying myeloma patients.

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September 10, 2015Clinical guidelines & position statements, IMWG, Library, Presentation & DiagnosisBy hparkin

Impact of cumulative bortezomib dose on overall survival: a retrospective analysis of VISTA trial data

This study, based on data from the VISTA trial, showed that cumulative bortezomib dosage affects response rate, time-to-progression and overall survival.

August 18, 2015Journal, LibraryBy webTeam Myeloma UK

IMWG updated criteria for the diagnosis of myeloma

This paper, produced by an expert panel of the International Myeloma Working Group (IMWG), provides consensus updates on the disease definition of myeloma which now include validated biomarkers in addition to the presence of the traditional ‘CRAB’ criteria.

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July 14, 2015Clinical guidelines & position statements, IMWG, Library, Presentation & DiagnosisBy MaggieLai

Diagnostic tests and prognostic indicators

Lipopolysaccharide-Induced CXCL10 mRNA Level and Six Stimulant-mRNA Combinations in Whole Blood: Novel Biomarkers for Bortezomib Responses Obtained from a Prospective Multicenter Trial for Patients with Multiple Myeloma. Watanabe T et al. PLoS One. 2015 Jun 26;10(6):e0128662. doi: 10.1371/journal.pone.0128662. High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma. Chhabra S et al. J…

June 30, 2015Diagnosing and Monitoring Myeloma, Journal, LibraryBy MaggieLai

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