Multiple myeloma presenting with acute bony spinal cord compression and mechanical instability successfully managed non-operatively. Gokaraju K et al. Spine J. 2016 Mar 17. pii: S1529-9430(16)00456-3. doi: 10.1016/j.spinee.2016.03.011. [Epub ahead of print]. Is balloon kyphoplasty safe and effective for cancer-related vertebral compression fractures with posterior vertebral body wall defects? Molloy S et al. J Surg Oncol. 2016 Mar 21. doi: 10.1002/jso.24222. [Epub…
International Myeloma Working Group Recommendations for the Diagnosis and Management of Myeloma-Related Renal Impairment. Dimopoulos MA et al. J Clin Oncol. 2016 Mar 14. pii: JCO650044. [Epub ahead of print]. Myeloma of the central nervous system – an ongoing conundrum! Harrison SJ et al. Leuk Lymphoma. 2016 Mar 21:1-2. [Epub ahead of print]. A case of multiple myeloma presenting as a distal renal tubular acidosis with extensive…
VTD is superior to VCD prior to intensive therapy in multiple myeloma: results of the prospective IFM2013-04 trial. Moreau P et al. Blood. 2016 Mar 21. pii: blood-2016-01-693580. [Epub ahead of print]. Intravenous (IV) bortezomib infusion after non-response to subcutaneous bortezomib administration can induce transitory responses in multiple myeloma patients: are some patients more sensitive to IV bortezomib? Gozzetti A et al. Br…
Allogeneic transplantation for multiple myeloma: yes, no or maybe? Bruno B et al. Bone Marrow Transplant. 2016 Feb 22. doi: 10.1038/bmt.2016.12. [Epub ahead of print]. Real-world outcome and healthcare costs of relapsed or refractory multiple myeloma: A retrospective analysis from the Chinese experience. Zhou X et al. Hematology. 2016 Feb 22. [Epub ahead of print]. Practical Approaches to the Management of Dual Refractory Multiple…
A comparison of the efficacy of piperacillin-tazobactam and cefoperazone-sulbactam therapies in the empirical treatment of patients with febrile neutropenia. Aynioglu A et al. Rev Esp Quimioter. 2016 Feb 16. pii: aynur16feb2016. [Epub ahead of print]. Retained needle after cement injection during vertebral augmentation and its management strategy. Kosse A et al. BMJ Case Rep. 2016 Feb 18;2016. pii: bcr2015012180. doi: 10.1136/bcr-2015-012180.…
Low serum vitamin D occurs commonly among multiple myeloma patients treated with bortezomib and/or thalidomide and is associated with severe neuropathy. Wang J et al. Support Care Cancer. 2016 Feb 23. [Epub ahead of print]. Early Postoperative Outcomes After Total Joint Arthroplasty in Patients With Multiple Myeloma. Menendez ME et al. J Arthroplasty. 2016 Jan 29. pii: S0883-5403(16)00091-7. doi:10.1016/j.arth.2016.01.029. [Epub ahead of print]. Bortezomib-based…
A phase 2 study of three low-dose intensity subcutaneous Bortezomib regimens in elderly frail patients with untreated multiple myeloma. Larocca A et al. Leukemia. 2016 Feb 22. doi: 10.1038/leu.2016.36. [Epub ahead of print]. A single-center retrospective analysis of first-line therapy of multiple myeloma with bendamustine-bortezomib-dexamethasone. Zwickl H et al. Leuk Lymphoma. 2016 Feb 22:1-6. [Epub ahead of print]. Stem Cell Harvesting after Bortezomib-Based Reinduction…
The National Institute of Health and Care Excellence (NICE) has set out new guidance for the diagnosis, treatment and care of myeloma patients with the aim of providing consistently excellent patient-focused care within NHS England. The new guidance has been created to cover aspects of management where in the past there was uncertainty or variation…
Multiple Myeloma: Diagnosis and Treatment. Rajkumar SV et al. Mayo Clin Proc. 2016 Jan;91(1):101-19. doi: 10.1016/j.mayocp.2015.11.007. Management of relapsed multiple myeloma: Recommendations of the international myeloma working group. Laubach J et al. Leukemia. 2015 Dec 29. doi: 10.1038/leu.2015.356. [Epub ahead of print]. First hematopoietic cell transplantation in Uzbekistan: Progress through education and cooperation. Karimov K et al. Transfus Apher Sci. 2016 Jan 12. pii: S1473-0502(16)00016-1. doi: 10.1016/j.transci.2016.01.014.…
Comparison of unilateral versus bilateral percutaneous kyphoplasty for the treatment of patients with osteoporosis vertebral compression fracture (OVCF): a systematic review and meta-analysis. Cheng X et al. Eur Spine J. 2016 Jan 27. [Epub ahead of print]. Pathophysiology of Metastatic Bone Disease and the Role of the Second Generation of Bisphosphonates:From Basic Science to Medicine. Barghash RF et…