Complications of myeloma and its treatments

Retrospective study of the incidence and patterns of arterial and venous thrombosis in Chinese versus African American patients with multiple myeloma. Raghupathy R et al. Br J Haematol. 2016 Jan 26. doi: 10.1111/bjh.13942. [Epub ahead of print]. Adventitious sporulation in Fusarium: The yeast that were not. Lockwood MB et al. IDCases. 2015 Dec 17;3:5-7. doi: 10.1016/j.idcr.2015.10.004. eCollection 2016. Bone Disease in Myeloma: The…

Current treatments

Triplet vs doublet lenalidomide-containing regimens for the treatment of elderly patients with newly diagnosed multiple myeloma. Magarotto V et al. Blood. 2016 Jan 4. pii: blood-2015-08-662627. [Epub ahead of print]. Lenalidomide plus melphalan and prednisone, followed by lenalidomide maintenance versus thalidomide plus melphalan and prednisone, followed by thalidomide maintenance; results of the randomised phase 3 HOVON 87/NMSG18 trial.…

Supportive care

Percutaneous vertebroplasty for patients with metastatic compression fractures of the thoracolumbar spine: clinical and radiological factors affecting functional outcomes. Bae JW et al. Spine J. 2015 Dec 2. pii: S1529-9430(15)01694-0. doi: 10.1016/j.spinee.2015.11.033. [Epub ahead of print]. Bone Marker-Directed Dosing of Zoledronic Acid for the Prevention of Skeletal Complications in Patients With Multiple Myeloma: Results of the Z-MARK Study.…

Current treatments

Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation. Ahmad I et al. Bone Marrow Transplant. 2015 Dec 21. doi: 10.1038/bmt.2015.319. [Epub ahead of print]. Phase I/II trial of Weekly Bortezomib with Lenalidomide and Dexamethasone in First Relapse or Primary Refractory Myeloma. Broijl A et al. Haematologica. 2015 Dec 11. pii: haematol.2015.132431. [Epub ahead…

Diagnostic tests and prognostic indictors

Imaging features of haematological malignancies of kidneys. Sandrasegaran K et al. Clin Radiol. 2015 Dec 11. pii: S0009-9260(15)00444-4. doi: 10.1016/j.crad.2015.11.007. [Epub ahead of print]. Minimal tumour burden in haematological diseases: a step forward with quantitative assessment of Bence-Jones in nephelometry? Pieri M et al. Br J Haematol. 2015 Dec 18. doi: 10.1111/bjh.13878. [Epub ahead of print]. ANNALS EXPRESS: Low IgA levels…

Related conditions

Clinical features and prognostic factors in solitary plasmacytoma. Finsinger P et al. Br J Haematol. 2015 Dec 18. doi: 10.1111/bjh.13870. [Epub ahead of print]. Immune status of high-risk smoldering multiple myeloma patients and its therapeutic modulation under LenDex: a longitudinal analysis. Paiva B et al. Blood. 2015 Dec 14. pii: blood-2015-10-662320. [Epub ahead of print]. Isolated Tricuspid Regurgitation: Initial Manifestation of Cardiac Amyloidosis.…

Emerging treatments

Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b-2 dose-escalation study. Richardson PG et al. Lancet Haematol. 2015 Dec;2(12):e516-27. doi: 10.1016/S2352-3026(15)00197-0. Epub 2015 Nov 16. Role of Histone Deacetylase Inhibitors in Relapsed Refractory Multiple Myeloma: A Focus on Vorinostat and Panobinostat. Afifi S et al. Pharmacotherapy. 2015 Dec;35(12):1173-88. doi:…

Biology and genetics

MTDH is an oncogene in multiple myeloma, which is suppressed by Bortezomib treatment. Gu C et al. Oncotarget. 2015 Dec 14. doi: 10.18632/oncotarget.6610. [Epub ahead of print]. Using “residual” FNA rinse and body fluid specimens for next-generation sequencing: An institutional experience. Wei S et al. Cancer Cytopathol. 2015 Dec 18. doi: 10.1002/cncy.21666. [Epub ahead of print]. miR-186 inhibits cell proliferation in multiple myeloma by…

General

Immunotherapy: the next step in the treatment of myeloma. Palumbo A et al. Lancet Haematol. 2015 Dec;2(12):e504-5. doi: 10.1016/S2352-3026(15)00226-4. Epub 2015 Nov 16. Mobilization policy in multiple myeloma: minimum target or law of redundancy? Two different approaches by the two sides of the Atlantic Ocean. Olivieri A et al. Bone Marrow Transplant. 2015 Dec 21. doi: 10.1038/bmt.2015.317. [Epub ahead of print]. Cohort Profile:…

Complications of myeloma and its treatments

Diffuse normolipemic plane xanthoma associated with monoclonal gammopathy. Cohen YK et al. Dermatol Pract Concept. 2015 Oct 31;5(4):65-7. doi: 10.5826/dpc.0504a16. eCollection 2015. Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature. Khan M et al. Urol Ann. 2015 Oct-Dec;7(4):530-3. doi: 10.4103/0974-7796.164844. Venous thromboembolism in hematopoietic stem cell transplant recipients. Chaturvedi S et…